Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity related to bortezomib, a proteasome inhibitor used in the treatment of various myeloma. Its synthesis or review is important for guaranteeing the purity and security of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor within the synthesis of abiraterone acetate, a drug used in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound inside the synthesis of imatinib, a drug that targets unique different types of cancer, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They're intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their examine is crucial for optimizing the manufacturing system and making certain higher purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilized to take care of breast most cancers, CAS NO.154229-19-3 and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the cure of breast most cancers. Different intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug powerful in managing cancers including ovarian, breast, and lung most cancers.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment of colorectal cancer and tiny cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, which have a variety of purposes, including antiviral Qualities.
Vildagliptin Intermediates: Utilized in the manufacture CAS NO. 122111-01-7 of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar stages.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated with the synthesis of varied gluconic acid derivatives, which might be Employed in food items, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A precursor while in the synthesis of canagliflozin, a medication utilised to handle sort 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).